News & Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Ken & Ruth Davee Department of Neurology.
04.25.2024A team of Northwestern Medicine investigators has discovered novel DNA methylation patterns in the blood of patients with Parkinson’s disease, findings that demonstrate the potential for using DNA methylation as a biomarker to identify the disease.
03.20.2024Northwestern Medicine investigators led by Amy Heimberger, MD, PhD, have discovered a new mechanism in which cancer-associated fibroblasts are associated with tumor grade and mediate immune suppression in glioma tumors.
03.08.2024Thrombolytic therapy administered longer after the onset of ischemic stroke than current recommendations did not demonstrate improved clinical outcomes as compared to placebo, according to a recent trial published in the New England Journal of Medicine.
02.14.2024A new study has found the immune system in the blood of Alzheimer’s patients is epigenetically altered, and many of these altered genes are the same ones that increase an individual’s risk for Alzheimer’s.
01.24.2024An experimental drug designed to block blood-clotting proteins may slightly lower the risk of recurrent strokes, according to a dose-finding trial published in The Lancet Neurology.
01.19.2024A new Northwestern Medicine study has identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains.
01.02.2024Northwestern Medicine investigators have discovered that specialized immune cells within the glioblastoma tumor microenvironment use a unique “feeding” mechanism that promotes tumor growth and treatment resistance, according to findings published in the journal Cell Metabolism.
12.11.2023An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, according to a Northwestern Medicine study published in Neuron.
12.04.2023Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences (PNAS).
11.30.2023Insertable cardiac monitors detected a higher incidence of atrial fibrillation in patients with prior ischemic stroke over a three-year period than standard medical monitoring methods, according to results published in JAMA Neurology, based on long-term findings from the Northwestern Medicine-led STROKE AF clinical trial.
11.15.2023A new Northwestern Medicine study has uncovered previously unidentified intracellular mechanisms in the peripheral nervous system that cause Charcot–Marie–Tooth Type 2B disease, findings that may inform the development of new targeted therapies.
11.10.2023A pair of recent studies from the laboratory of Evangelos Kiskinis, PhD, have uncovered novel cellular mechanisms that are involved in two types of genetic ALS, providing support for future development of targeted therapies to treat the disease.
10.26.2023Scientists have uncovered a genetic explanation for a subset of common brain tumors, according to a study published in Nature Communications.
09.28.2023A new Northwestern Medicine study has demonstrated how differences in neural activity within the brain’s olfactory and orbital cortices cause people to perceive the same odors differently, according to findings published in Nature Neuroscience.
09.18.2023A new study suggests that a dysfunction in neurons’ synapses leads to deficits in dopamine and precedes the neurodegeneration previously thought to cause Parkinson’s disease.
- 08.25.2023
An experimental drug targeting a genetic variant linked to Parkinson’s disease had no effect on patients, according to the results of a new clinical trial published in The Lancet Neurology.
08.15.2023The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a renewed five-year $10.8 million Specialized Program of Research Excellence (SPORE) grant from the National Cancer Institute for the Lurie Cancer Center to advance translational research and improve outcomes for patients with brain cancer.
08.03.2023A new Northwestern University-led study published in Nature Neuroscience has discovered that dopamine neurons are more diverse than previously thought, opening new research directions for further understanding and potentially even treating Parkinson’s disease.
07.21.2023Northwestern Medicine scientists have uncovered a new mechanism by which mutations in a specific gene contribute to familial forms of Parkinson’s disease, which opens an avenue for new therapeutics.
07.13.2023A recent Northwestern Medicine study has revealed that the brain’s temporal pole has critical functions in word comprehension, face recognition and the regulation of behavior.
05.17.2023A team led by Northwestern Medicine investigators have discovered novel cellular mechanisms that lead to chemotherapy resistance in recurrent glioblastoma, according to findings published in Science Advances.